MagnetOs™ Putty

Seller: Revolution Surgical

SKU: 703-029-AU

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Description

A bone graft like no other

MagnetOs™ is a bone graft like no other: thanks to its NeedleGrip™ surface technology, it grows bone even in soft tissues.* This surface technology provides traction for our body’s vitally important ‘pro-healing’ immune cells (M2 macrophages).

This in turn, unlocks previously untapped potential to stimulate stem cells – and form new bone throughout the graft.

The growing body of science behind NeedleGrip is called osteoimmunology. But for surgeons and their patients it means one thing: a more predictable fusion.

MagnetOs Mechanism of Action

1. Polarise

Circulating immune cells (monocytes) differentiate into macrophages that are subsequently polarised, by the submicron needle-shaped features of MagnetOs’ NeedleGrip surface.

As a result, they become the pro-healing, anti-inflammatory M2 macrophage phenotype.

2. Regenerate

In natural bone homeostasis, it is well established that M2 macrophages play a critical role.

M2 macrophages communicate with local stem – and progenitor cells via secretion of regenerative signalling factors, including osteoactivin and BMP-2.

These signalling factors induce mesenchymal stem cells to migrate, proliferate, and differentiate into osteoblasts that lay down osteoid.

Endothelial cells are stimulated to form capillaries that deliver nutrients and yet more osteogenic cells to the site of repair.

3. Propagate

Non-unions tend to happen in the core of large-span defects, as seen in spinal fusions.

NeedleGrip propagates bone in this core region – by interacting directly and indirectly with circulating osteogenic cells – rather than only from the outside-in via creeping edge repair.

MagnetOs Putty

Speed and efficiency are essential in the operating room, which is why we designed MagnetOs™ Putty to be easy to store, handle, and apply. 

MagnetOs Putty delivers all the benefits of our established MagnetOs family thanks to our unique NeedleGrip™ surface technology – which grows bone even in soft tissue* without added cells or growth factors.

Simply warm it in your hands, mold into the desired shape, and use it to fill bony voids spaces any way you need, including in the intervertebral disc space or posterolateral spine.